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Recently, peptides that target next-generation immune checkpoints, such as T-cell immunoglobulin-3 (TIM-3), lymphocyte activation gene 3 (LAG-3), and T-cell immunoreceptor with Ig and ITIM domains (TIGIT), have attracted increasing attention

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In cancer cells, it induces cytotoxicity, but in normal cells, it results in lipoperoxidation, inflammation, and exacerbation of unfavourable effects during therapy [26, 27]

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