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In these cases, the evidence relies on a combination of studies showing the dysregulatory effect of smoking and/or cigarette smoke constituents on the above factors and studies showing the pathogenetic effect of these factors on various non-communicative diseases

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They look like cigarettes, and offer the feel of smoking a cigarette, without the smoke or the tobacco

Moreover, orexin-A levels were significantly lower in never smokers with OSAHS compared to ex- or current smokers [114]

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