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1997 saw the advent of the Master Settlement Agreement (MSA), which imposed massive restrictions on tobacco companies ability to market their products

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Proc Natl Acad Sci U S A

The rapid increase in non-combustible tobacco use among younger adults reflects the growing popularity of ECs and supports the idea that ECs are replacing cigarettes as the main type of tobacco product consumed 1,9

Bibliography [edit] Abrams, David B., et al