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Clinical Evidence: Research shows high-dose B12 therapy can greatly improve neurological function in severe cases

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How often you get these shots depends on how bad the deficiency is and how well you react to treatment

As prescribed by the doctor, many benefits can be felt if the shot is taken for around 2 to 3 months

The 2026 Sports Medicine and JAAOS Global Research and Reviews papers (PMID 41966639, PMID 41490200) place multiple compounds including this one into the wider research context of unapproved compounds under active investigation, with attention to both the mechanism findings and the regulatory framing that researchers consulting these reviews should weigh equally