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DOI: 10.1056/NEJMoa2502081 Davies MJ, Bajaj HS, Broholm C, Christiansen E, Fink LN, Hussein Z, et al

Glycemic and metabolic markers: Trial disclosures describe improvements in glycemic control and cardiometabolic measures alongside weight loss, with cardiovascular outcomes still under study in REDEFINE 3 [8]

These came up short of expectations, but there were also winners -Bristol Myers Squibbs LAG3 (Opdualag) + CTL4 (Yerovy), both of which are expected to be multi-billion dollar drugs

The exact amount depends on the patients health, how bad the deficiency is, and how well they respond to treatment

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