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The manual's section 10.1 sets the pairing rule clearly: use Lumo+ before microinfusion on the same session day (warms tissue, primes circulation), wait at least 24 hours after microinfusion before resuming any RF or EMS device (heat on freshly opened channels amplifies redness and disturbs early healing), and use Lumo+ on its normal schedule of 3 to 5 sessions per week on non-microinfusion days

TLR4, rather than TLR2, regulates wound healing through TGF-beta and CCL5 expression

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H.PetrovicA.et al (2020b)

Upregulated genes were enriched in pathways related to T cell differentiation and activation (for example, RUNX3 , IFNG , TNFSF9 ), negative regulation of the immune response (for example, WASL , ID2 , TNFAIP3 ) and circadian regulation of gene expression (for example, RORA , PER1 , NRIP1 ) (Fig