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When you're dehydrated, your body's ability to function properly is compromised, making you feel worse

Sunlight exposure also provides additional support for healthy blood pressure by stimulating the production of nitric oxide, which helps relax blood vessels

It is also possible that in active acromegaly, chronic exposure to elevated IGF-I levels resets IGF-IR responsiveness via the induction of IGF-IR resistance (70), as it has been demonstrated that prolonged stimulation with IGF-I induces functional IGF-IR resistance in vitro through the negative feedback loop (72)

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