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Iron deficiency anemia tends to produce pallor rather than dark spots, but B12 deficiency has been associated with diffuse lip hyperpigmentation in clinical literature

Still, "safe" depends on the individual cat, the full ingredient list, and whether there are underlying conditions or medications involved

Parabiosis studies revealed that the presence of systemic inflammation in the aged environment impedes neurogenesis

One may consider switching to antiretroviral agents with lower propensity for causing hyperlipidaemia provided that viral control is not jeopardised

6c, d and Supplementary Fig