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Beyond the well-established roles of histamine, IL-31, and neuropeptides in sensory modulation, purinergic signaling mediated by ATP has recently emerged as a critical complementary pathway in the sensitization of the mast cellneuron axis in AD, with particular attention to the P2X3 receptor

However, as we are a remote island nation with unique ecosystems, the shortage of specific evidence for Aotearoa makes it challenging to understand how our ecosystems might respond to air pollution and how sensitive they are to damage

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Its been frustrating from that standpoint, because its been legal for close to six years now, said Brett Scolari, a lobbyist who represents several marijuana businesses in the state