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In clinical treatment, it is necessary to choose the oncolytic HSV-1 with silent gene 134.5 according to the tissue source of the tumor

PARP-1 (poly-ADP-ribose polymerase 1) is a DNA repair enzyme that consumes NAD + to synthesize poly-ADP-ribose chains at damage sites

Pampliega O, Domercq M, Soria FN et al (2011) Increased expression of cystine/glutamate antiporter in multiple sclerosis

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The diversity in the responses of individuals is the main reason for this

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