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Change history 30 May 2024 A Correction to this paper has been published: References Chou KL, Stacy M, Simuni T, Miyasaki J, Oertel WH, Sethi K, Fernandez HH, Stocchi F (2018) The spectrum of off in Parkinsons disease: What have we learned over 40 years

It is composed of three amino acids: cysteine, glutamine, and glycine

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Dichloroacetate Dichloroacetate (DCA), a product of water chlorination, is considered for the treatment of several disorders including genetic mitochondrial diseases and some hyperproliferative conditions 82

A chaotic process invites error

Standard oral formulations achieve only 0.7% bioavailability, limiting blood level increases compared to IV delivery