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To fully identify and elucidate complex mechanisms of action, intervention studies that assess markers related to these pathways within clinically diagnosed human populations are needed

Histidine can be used in the body for several different purposes, including histamine production, metal ion chelation, and neutralizing ROS

PMID: 21168117.

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The anti-schistosomal drug praziquantel is an adenosine antagonist

From the limited research that exists, they are probably safe to consume