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Such studies could enhance the safe use of one of the most frequently taken drugs

Mol Biol Rep 41:49194927 Diaz-Vivancos P, de Simone A, Kiddle G, Foyer CH (2015) Glutathione-linking cell proliferation to oxidative stress

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There are many reasons why someone may have poor glutathione status: Low precursors (cysteine, glutamate, glycine) Chronic oxidative burden and/or inflammation Deficiencies in the nutrients required to generate, process, or utilize glutathione (B6 or selenium) A total and/or functional riboflavin deficiency is the probably the most common culprit responsible for poor glutathione reductase activity