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Participants randomly received an e-cigarette that delivered 36, 8 or 0 mg/mL of nicotine, or a cigarette substitute that contained no tobacco, as an aid in their efforts to reduce their cigarette consumption

e-cigarettes are marketed as an effective approach for reducing conventional cigarette consumption and smoking cessation [14, 15]

This includes two new low-nicotine Pinnacle VLN cigarette products alongside two moist snuff flavors, rolled out in late summer and fall 2025, pending state approvals