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doi: 10.1001/jamapsychiatry.2023.0685 181 MilaneschiYSimmonsWKvan RossumEFCPenninxBW

A double-blind, placebo-controlled trial in 90 HIV-positive patients with symptomatic distal symmetrical polyneuropathy found no benefit of intramuscular injection with 1 g/day of ALCAR for two weeks in the intention-to-treat analysis, but there was some pain relief in the group of 66 patients who completed the trial (84)

Ipamorelin acts at the pituitary level through GHS-R1a, while CJC-1295 stimulates GH release through the GHRH receptor a separate signalling pathway that works synergistically with ghrelin receptor activation

Mingrone G

Q: What happens if I take a break mid-protocol