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DOI: 10.4103/0028-3886.236968

Biochimica et Biophysica Acta, 1741 (1-2), 4854

Research indicates that oxidative stress (OS), inflammatory responses, and lipid metabolic disturbances induced by alcohol and its metabolites are primary contributors to hepatocyte injury, positioning OS as a key target in ALD treatment

BaP/BPDE suppressed endothelial cell angiogenesis to induce miscarriage by promoting MARCHF1/GPX4-mediated ferroptosis

Statistical analysis was performed using two-way ANOVA ( g,j,o ) or unpaired two-tailed t-test ( r )

identified proteins that are critically relevant in T21 pathogenesis and are involved in iron homeostasis (ceruloplasmin and transferrin), lipid metabolism (zinc-a2-glycoprotein, retinol-binding protein 4, and apolipoprotein A1), and inflammation (complement C9,a-1B-glycoprotein, collagen alpha-1 V chain) (Perluigi et al