Methods The study was an open label, single arm, multicenter, pilot trial
387, Oct
However, this study did not directly confirm whether PMSCs migrated to the ovaries
Role of iron metabolism in heart failure: From iron deficiency to iron overload
Currently, DRESS is considered a serious, idiosyncratic adverse drug reaction, mediated especially by T-cells, classified as a type IVb hypersensitivity reaction (sometimes IVc), according to the Gel & Coombs classification, expanded by Pichler.21 Thus, the current concept is that DRESS is the result of the complex interaction between exposure to medications (or immunizing vaccines, or immunobiologicals), genetic predisposition, and reactivation of latent viruses, particularly from the Herpesviridae family.20 The reason why some individuals develop this adverse reaction, while others do not, despite being exposed to the same medication, seems to result from the cumulative effect of the conjunction of risks, which are aligned through a single successive causal model, where the final result, in a straight line, is DRESS (Fig
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