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Nutraceuticals and Diet-based Phytochemicals in Type 2 Diabetes Mellitus: From Whole Food to Components with Defined Roles and Mechanisms

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Extensive studies have focused on changes in the peri-infarct region, including activation of an axonal sprouting program, cellular composition changes (astrocyte and microglia proliferation/migration), and neurophysiological properties [84, 85]

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76 A key challenge remains the high cost of third generation IV iron formulations, although there are potential savings in clinic personnel time and bed space