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Once widespread rod cell death has occurred, cone photoreceptors gradually degenerate, causing visual loss and complete blindness

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[DOI] [PMC free article] [PubMed] [Google Scholar] Balchandani P., Naidich T.P

the oxidized form (glutathione disulfide, GSSG) is not used in supplements [1]

However, randomized controlled trials are needed to determine whether antioxidant supplements slow or prevent age-related cognitive decline

[] Despite all these drawbacks, -LA and DHLA are considered promising metal chelators and potential antioxidants with both of these compounds meriting further detailed investigations to determine their safety profiles in clinical applications