Users who have tried minoxidil without satisfactory results represent another good candidate population
The original 2015 Cell Metabolism study demonstrated that intraperitoneal MOTS-c injections (5 mg/kg) in mice fed a high-fat diet prevented obesity and insulin resistance, with effects on fat mass, fasting glucose, and insulin sensitivity that rivaled pharmaceutical intervention [1]
In fact, it has been demonstrated that several molecules secreted by beta cells, such as insulin, zinc, and c-aminobutyric acid, inhibit the secretion of glucagon
If you have a history of allergies or have had a reaction to a supplement in the past, it is important to talk to your doctor before taking a B complex supplement
However, regular supplementation is necessary to maintain optimal levels and prevent deficiency from occurring again
Low responders may benefit from switching to oral minoxidil under medical supervision, which bypasses the follicular conversion step, though this introduces different risk considerations