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Future research must focus on longitudinal human studies and multi-omics approaches to elucidate mechanistic details and develop effective clinical interventions for preventing and managing systemic diseases linked to oral-gut microbial dysbiosis

A phase 1 study of pegylated Recombinant arginase (PEG-BCT-100) in combination with systemic chemotherapy (capecitabine and oxaliplatin)[PACOX] in advanced hepatocellular carcinoma patients

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Vitamins serve as essential micronutrients that maintain intestinal homeostasis by modulating the gut microecology and preserving epithelial barrier integrity 205

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