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Insulin levels stayed stable

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Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking

Lidocaine is not approved for this use (see WARNINGS and DOSAGE AND ADMINISTRATION)

indicated that the peptide reduced over 50% of body weight gain in these laboratory models compared to controls, with heightened lipolytic activity observed within the adipose tissues of exposed rats, alongside an absence of notable disruptions in insulin sensitivity in these experimental settings