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Mr Monu received fellowship support from CSIR, New Delhi

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It has been found that mutation in ZnT8 may contribute to dysregulation in insulin in the first passage through the liver and increase risk of type 2 diabetes mellitus development [136]

There is also an observed potential decrease in the activity of enzymes that facilitate the urea cycle

The clinical spectrum of COVID-19 ranges from mild respiratory symptoms to severe disease manifestations, including pneumonia, acute respiratory failure, multiorgan failure, and death (115)

The three most frequent hyperpigmented disorders include actinic (AL) or solar (SL) lentigines [20,21,22,23,24], PIH [25,26,27], and melasma [28,29,30,31], all sharing an increase in melanin content but each also being characterized by specific features (Fig