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The therapeutic scope of probiotics extends to metabolic health, with oral supplementation of Bifidobacterium breve improving glycemic control in T2DM and Anaerobutyricum soehngenii enhancing intestinal barrier function through SCFA production, improving metabolic indicators in prediabetes (Shetty et al., 2020

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37 Most reports estimate the prevalence of painful DPN (PDPN) among diabetes patients to be between 13 and 35%