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The pineal gland produces melatonin, the hormone that regulates sleep-wake cycles

PEA (palmitoylethanolamide) is a natural compound your body already makes

This medication is manufactured as a sterile topical solution, which is intended for administration in the eyes

References & Further Reading Sikiric, P

During administration, the animals were maintained in a head-tilted position, and gentle pressure was applied to the nasolacrimal duct at the inner canthus for approximately 1 minute to prevent drainage of the solution through the nasolacrimal passage

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