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High NO concentration proved to have anti-apoptotic effects and to protect cell survival, whereas decreased iNOS expression and low NO concentration induced apoptosis by activating the caspase-mediated cascade in in vitro cultured granulosa cells

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Bioavailability has also been directly assessed by measuring polyphenol concentrations in plasma and urine after ingestion of purified compounds or polyphenol-rich foods (114)

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Des tudes n'ont rvl aucun effet secondaire grave chez les personnes prenant jusqu' 500 mg par jour pendant deux mois