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In neurodegenerative diseases, including Alzheimers disease and Parkinsons disease, studies have detected gut microbial imbalance (155, 156)

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Within days of starting anti-hypertensive medication therapy, kidney damage can also happen from Angiotensin converting enzyme (ACE) inhibitors, -blockers, NSAIDS/selective cyclooxygenase II (COX-2) inhibitors, cocaine, and occupational toxins 11

Most sublingual peptide formulations should be refrigerated