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Genistein was shown to modulate angiogenesis in human and mouse endothelial cells and induce macrophage polarization to a pro-repair phenotype, two important processes during physiological wound healing (Peng et al., 2023)

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Importantly, selective toxicity of the agent against ATC cells over normal thyroid cells were observed

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Ebselen was found to increase the expression of GPX1 in SGNs after peroxynitrite damage, which is consistent with the reports that ebselen can increase the expression of GPX1 in cochlea after electrical stimulation ( gpx1 / mice leads to the aggravated SGN injury (cell loss and apoptosis) induced by peroxynitrite, although it might cause no effect on SGN development as SGNs presented normal morphology and cell number in gpx1 -deficient mice