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In recent years, intranasal (IN) drug delivery has emerged as a promising strategy to bypass the BBB, providing a direct nose-to-brain delivery route via olfactory and trigeminal pathways while minimizing systemic exposure

doi:10.1093/oxfordjournals.aje.a112428

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HPLC and Mass Spectrometry Considerations for Blends Standard reversed-phase HPLC of a four-component blend produces a multi-peak chromatogram