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This would allow for mechanistic decoupling of IFN induction via phosphorylated STING and proton channel-dependent LC3 lipidation and inflammasome activation (164)

Adipose tissue as an endocrine organ: from theory to practice

On the other hand, some carbohydrates, such as galactooligosaccharides, can support the growth of beneficial bacteria, and dietary fiber has been shown to positively affect intestinal permeability [7]

In a study on the efficacy and safety of catalpol in the treatment of postoperative patients with locally advanced colon cancer, patients treated with an intraperitoneal injection of 10 mg/kg catalpol twice a day for 12 weeks, monitoring patients appeared with adverse reactions of diarrhea, nausea, vomiting, gastrointestinal ulcers, allergy, constipation, alopecia, and peripheral neurotoxicity

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Kim H, Kim D, Choi SA, Kim CR, Oh SK, Pyo KE, Kim J, Lee SH, Yoon JB, Zhang Y, Baek SH