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Treatment with NNMT inhibitors rescues these age-related deficits by restoring NAD+ availability and supporting metabolic reprogramming during myogenic differentiation

Monitoring considerations: HbA1c and fasting glucose (for T2DM patients) at 3-month intervals

Evaluation of production: type II collagen, aggrecan, MMP-13 (degradation enzyme), IL-1 response

B Complex Vitamins Promote healthy cell turnover and improve hydration

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Serious Complications (Very Rare): Extremely rare but possible severe side effects can include congestive heart failure in individuals with certain heart conditions, or polycythemia vera (a blood disorder)