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Shaking creates aggressive mechanical forces that can break the delicate peptide bonds and denature the molecule, rendering it inactive

It markedly reduces ROS and malondialdehyde (MDA) levels, restores glutathione balance, and up-regulates the expression of Nrf2 and its downstream effector HO-1

The Prevalence and Indications of Intravenous Rehydration Therapy: A Systematic Review Source: PMC (PubMed Central) Summary: A systematic review that quantifies how often IV rehydration is used (especially in pediatric and adult populations) and for which clinical indications (e.g., diarrhea, influenza, GI losses), is helpful background for comparing wellness IV hydration to medical standards

J Endocrinol 184(3): 455-465

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