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Ashley et al., 2012

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Sildenafil increases muscle protein synthesis and reduces muscle fatigue

Strinic et al., BPC 157 counteracts QTc prolongation induced by haloperidol, fluphenazine, clozapine, olanzapine, quetiapine, sulpiride, and metoclopramide in rats, Life Sci., vol

Their combination theoretically offers a dual ferroptosis-inhibitory mechanism via concurrent Nrf2 activation and AMPK/ACSL4 suppression, particularly relevant in neurodegenerative contexts like AD

Graphical Abstract Similar content being viewed by others Background Equine metabolic syndrome (EMS) is an endocrine disorder observed in obese horses, primarily characterized by insulin resistance (IR), laminitis, and abnormal fat distribution