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This review examines the role of gut microbiota in the pathogenesis of common gastrointestinal diseases and explores emerging therapeutic approaches aimed at modulating the microbiome

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Future frameworks will likely need to incorporate guidance for engineered strains, synbiotics, microbial consortia, and microbiome-based therapeutics, extending the FAO/WHO principles to more complex products while maintaining their core focus on strain specificity, safety, and evidence-based health benefits (531)

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