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Chung, J.Y., J.H

[ Acknowledgements We thank Sven Paul, Institute of Animal Breeding and Husbandry, University of Kiel, for revising the manuscript, Matthias Leippe, Department of Zoophysiology, University of Kiel, for helpful information and Virbac for providing the picture "Internal organs of the horse"

Jones et al 19

Regardless of the animal model, all studies have demonstrated the beneficial effects of caffeine with antidepressant and anti-inflammatory actions

When tumors achieved a size of 100 mm 3 , mice were randomized into four groups

Most patients tolerate both therapies well when administered under clinical supervision