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LaCourse EJ, Perally S, Morphew RM, Moxon JV, Prescott M, Dowling DJ, et al

Combination Therapy: Some patients benefit from taking both alpha blockers and 5-alpha reductase inhibitors for a more comprehensive approach

This regulatory activity may support endothelial function and promote vessel relaxation, contributing to improved hemodynamic balance in experimental settings

Ann Surg Oncol 28(13):8485-8494, 2021

Adding less water will create a more concentrated solution (more mcg per unit), while adding more will make it more dilute