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Inhibition of lipid oxidation increases glucose metabolism and enhances 2-deoxy-2-[(18)F]fluoro-D-glucose uptake in prostate cancer mouse xenografts

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In particular, one study (NCT06437574) is evaluating whether intensive cholesterol reduction with oral simvastatin and ezetimibe enhances CD8 + memory T cells and promotes CD8 + T cell infiltration into prostate tissue