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10.2174/1566524015666150114111258 178 Srensen-ZenderI.BhayanaS.SusnikN.RolliV.BatkaiS.BaisantryA.et al (2015)
The strategies to address senescent cells and replenish exhausted stem cells during the aging process, as well as supplementing metabolic substances like NAD+, gene therapy, or epigenetic approaches to mitigate aging, are different because they aim to promote the repair of senescent cells rather than inducing their apoptosis (Covarrubias et al., 2020
It is hypothesized that this action might be associated with increased activity of antioxidant enzymesproteins that help protect cells from damage due to oxidative stress
Oxidized glutathione is regenerated to GSH through glutathione reductase in an NADPH-dependent process, enabling continuous antioxidant activity
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