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Controlled uncoupling with modified dinitrophenol analogs (e.g., DNP-Mito) reduced mtROS by 65% while maintaining ATP synthesis in hypertensive rat models (Kotova and Antonenko, 2022)

The bulk of evidence is pre-clinical, concentrated in skin, wound-healing, and hair-follicle research

Puede requerir ajuste de dosis de medicamentos concomitantes

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