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For survival analysis, the mice were closely monitored on a daily basis, and the size of tumors was measured with a caliper every 4-5 days

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In advanced fibrotic stages, saponins (e.g., ginsenoside Rg1) and low-dose anthraquinones (e.g., emodin) delay collagen deposition by modulating the gut-liver axis and suppressing TGF-1/Smad3 signaling (Yang et al., 2022)

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