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doi: 10.1074/jbc.M708096200

In patients with residual CBS activity (between 0% and 2% of normal), approximately half of the cases of homozygous homocystinuria, pyridoxine treatment can decrease the hyperhomocysteinemia

in this regard, vitamin B 12 is the only exception as the development of deficiency generally takes much longer time (Reference McNulty, Pentieva, Geissler and Powers3)

Abstract Glutathione transferase classical GSH conjugation activity plays a critical role in cellular detoxification against xenobiotics and noxious compounds as well as against oxidative stress

Since SARS-CoV-2 activates mitochondrial ROS-mediated feedback loops that produce long-term changes in the redox status and endothelial function of the host, leading to cardiovascular disease and lung injury (Chang et al., 2021), and endothelial cells are key players in inflammatory pathologies, such as acute respiratory distress syndrome, thrombosis, and atherosclerosis

Azzarelli R, Guillemot F, Pacary E