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Nature Communications , 4 , 2516

S -glutathionylation, a redox-dependent posttranslational modification of a protein, accounts for the reversible regulation of the structure and function of a variety of proteins that are integral to cell structure, signaling, and metabolism

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For instance, by reshaping the balance between Th17 and Treg cells, selective inhibition of GOT1 with (aminooxy)acetic acid (AOA) ameliorates experimental autoimmune encephalomyelitis in mice ( + T cell differentiation, has enormous promise as a target for therapeutic intervention

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