The number of additives is so large, and the chemical mixtures produced by cigarettes so complex, that measuring effects of individual additives is difficult, and expensive
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However, even 100 g/g is still not enough to replace cigarettes, vape, or snus
And that, of course, can raise your risk of heart attack or stroke
Table 2 shows the results of these studies with the exception of the study of Kozlowski, because we were not able to retrieve its results [6]
The studies addressed attrition in a number of ways, including (1) comparing associations with complete case analysis to results from analysis using maximum likelihood estimation methods (Wills et al., 2016b), (2) using alternative assumptions that all lost to follow-up are either initiators or non-initiators (Leventhal et al., 2015), and (3) using auxiliary variables to estimate and impute outcome data (Primack et al., 2015)