Nuclear factor erythroid 2-related factor 2 (Nrf2) is a crucial redox-regulated gene in controlling ROS levels
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Sirtuin3 (sirt3) is a deacetylase located in the mitochondrial matrix, participating in the SUMO-specific protease (SENP1)-Sirt3 axis to regulate the metabolic activity of mitochondria together with its upstream protein SENP1
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This deactivation of MKPs allows for the unimpeded progression and sustained activation of the pro-inflammatory ERK1/2, JNK, and p38 signaling cascade within the MAPK pathway (Son et al., 2011)
Olive oil-supplemented diet alleviates acute heat stress-induced mitochondrial ROS production in chicken skeletal muscle