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AHK-Cu then provides copper ions for lysyl oxidase, the enzyme that permanently stabilizes new collagen through cross-linking

A brief stinging or burning sensation at the injection site is a commonly reported and chemically explainable reaction to GHK-Cu injection

The UAE process resulted in a maximum TPC of 181.51 mg GAE/g DE, CUR of 604.40 mg/g DE, highlighting a high inhibitory potential for AChE (IC 50 : 5.21 g/mL) and LOX (IC50: 17.96 g/mL)

However, their effectiveness in achieving skin-lightening or similar benefits is still a subject of debate within the scientific community

J Investig Allergol Clin Immunol 1998

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