The two termsGSH and glutathionetend to be used interchangeably
The specific sequence of glycine, histidine, and lysine in GHK-Cu is fundamental to its unique three-dimensional structure and ability to bind copper, which in turn dictates its biological function
Sinauer Associates
In intact skin without a penetration enhancer (such as ethosomes, liposomes, or hyaluronic acid conjugation), multiple ex vivo tape-stripping studies show that most topically applied GHK-Cu accumulates in the stratum corneum and upper viable epidermis, not in the dermis where fibroblasts live
It is a synthetic peptide that primarily aids in tissue repair, vascular regeneration, and reducing inflammation
Its unique peptide sequence confers resistance to enzymatic degradation, thereby facilitating its study in various experimental models