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Activation of Nrf2 and a subsequent induction of GCL have been reported for various oxidants and electrophiles such as DEM, H 2 O 2 , quinones, 4-hydroxynonenal, methyl mercury, arsenicals, and plasmonic gold nanoparticles (Zhang et al

The limited follow-up and the absence of adjustments for confounding variables further constrain the robustness and generalizability of the findings

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10.1016/j.ejphar.2021.174096 100 TizabiY.HurleyL