Although in our study roGFP2 expressed in the cytosol or in the plastid exhibited reduced fluorescence intensity upon AITC treatment, it is currently not known if AITC can hijack glutathione only in the cytosol and therefore interrupt the nuclear import, or is able to deplete different pools at the same time
Safety and long-term effects are still topics of scientific investigation
J Amino Acids 2012:736837 Guloyan V, Oganesian B, Baghdasaryan N, Yeh C, Singh M, Guilford F, Ting YS, Venketaraman V (2020) Glutathione supplementation as an adjunctive therapy in COVID-19
Prdxs are divided into the subgroups Prdx1/AhpC, Prdx5, Prdx6, Tpx (thiol peroxidase), PrdxQ/BCP, and AhpE
Before the first injection, the vial must be reconstituted
Perfusion was performed by flushing pre-warmed RPMI containing phenol red and L-glutamine through a 25- and 3/8-gauge needle placed into the aorta attached to Tygon tubing aided by the Masterflex L/S perfusion pump as described 81