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With mouse models not being able to accurately recapitulate human neurodevelopmental periods, another translational step could be developing models of haploinsufficiency within NHPssomething that has already been established for the SHANK3 and MECP2 genes within cynomolgus macaques [35, 36]
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Inhibition of insulin-regulated aminopeptidase (IRAP) by arylsulfonamides