6.1 SCFA Imbalance: Propionate Elevation and Butyrate Deficiency Short-chain fatty acids (SCFAs), primarily acetate, propionate, and butyrate, are microbial metabolites with broad effects on mitochondrial function, immune regulation, and gene expression
Appetite and sleep changes Self-reported appetite shifts (in both directions) and altered sleep difficulty falling asleep, lighter sleep, or vivid dreams are described inconsistently across community sources, with no documented dose relationship
It is frequently examined in studies focused on adipose-cell signaling, energy balance, and metabolic efficiency, where researchers investigate how modulation of NNMT activity affects cellular behavior and downstream biological responses
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Milton, R
Griffith AV, Venables T, Shi J, Farr A, van Remmen H, Szweda L et al (2015) Metabolic damage and premature thymus aging caused by stromal catalase deficiency
